Pleural Mesothelioma Symptoms
The symptoms of pleural
mesothelioma, a type of mesothelioma
that originates in the two layers that make up the lining of the lungs and
chest wall (known as the pleura), are most often caused by the tumors that form
within these layers. These tumors form, over time, after asbestos inhalation
has occurred. When asbestos fibers are inhaled, they make their way through the
trachea or bronchi and eventually penetrate the pleural lining. These asbestos
fibers may then damage the DNA of mesothelial cells, causing uncontrolled cell
growth and the development of mesothelioma, which leads to the symptoms below.
Roughly 60% of patients
diagnosed with pleural mesothelioma report lower back or side chest pain. There
are also frequent instances of shortness of breath. Some people may experience
difficulty swallowing, a persistent cough, fever, weight loss, or fatigue.
Additional symptoms include muscle weakness, loss of sensory capability, hemoptysis or coughing up blood, facial and arm swelling,
and hoarseness.
Pleural mesothelioma is
also the only type of mesothelioma that is formally classified into stages. The symptoms that accompany these
stages depend largely on the size and location of tumors and if any form of
fluid buildup is present.
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